Status:
COMPLETED
Oral Surgery in Patients Taking Direct Oral Anticoagulants
Lead Sponsor:
University of Novi Sad
Conditions:
Anticoagulants and Bleeding Disorders
Surgery
Eligibility:
All Genders
18+ years
Brief Summary
This study evaluates the incidence of postoperative bleeding after oral surgical procedures in patients taking direct oral anticoagulants and in patients taking vitamin K antagonists.
Detailed Description
Vitamin K antagonists (VKA) are widely used in long term prevention and treatment of thromboembolism. In the last few years direct oral anticoagulants (DOACs) are available for clinical use, mostly in...
Eligibility Criteria
Inclusion
- Male and female patients over 18 years
- Patients taking regularly direct anticoagulant therapy: dabigatran, rivaroxaban or apixaban (DOACs group)
- Patients taking regularly acenocoumarol with INR 2.0-3.5 on the day of the surgery (VKA group)
- Indication for oral surgical procedure
- Signed informed consent
Exclusion
- Liver or renal disease
- Coagulopathy
- Pregnant or breastfeeding women
- Allergy to lidocaine
- Patients who stopped taking their anticoagulant medication
- Patients taking VKA with INR \<2.0 or \>3.5 on the day of the procedure
Key Trial Info
Start Date :
May 25 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 3 2020
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT04505475
Start Date
May 25 2015
End Date
August 3 2020
Last Update
August 13 2020
Active Locations (1)
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1
Dental Clinic of Vojvodina
Novi Sad, Vojvodina, Serbia, 21000