Status:
UNKNOWN
Acetated Ringer's Solution Versus Saline in Patients With Septic Shock
Lead Sponsor:
Southeast University, China
Conditions:
Septic Shock Hyperdynamic
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
The primary aim of this trial is to compare the effect of acetated ringer's solution with that of saline for therapy on the incidence and development of major adverse renal events among septic shock p...
Detailed Description
Normal saline and Ringer's solutions are the preferred crystalloid fluids administered in early septic shock. However, evidence have associated saline with hyperchloremia and secondary metabolic acido...
Eligibility Criteria
Inclusion
- Adult patients presenting to the ICU diagnosed as septic shock within 24 hours.
Exclusion
- Pregnancy;
- Likely requirement for immediate hemodialysis or renal replacement therapy;
- Patients have already received fluids for more than 4 liters;
- Patient in extremis or death deemed imminent and inevitable.
Key Trial Info
Start Date :
September 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT04507672
Start Date
September 1 2020
End Date
December 1 2023
Last Update
August 11 2020
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