Status:

COMPLETED

Combined Deep Inspiration Breath Hold (DIBH)-Expiration Planning Technique in Patients With Lung Tumors in Close Proximity to the Chest Wall

Lead Sponsor:

Indiana University

Conditions:

Lung Cancer

Metastatic Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate a new radiation planning and treatment delivery technique called Deep Inspiration Breath Hold (DIBH) and expiration technique. This technique will be used to t...

Detailed Description

Multiple studies have evaluated the efficacy of SBRT in patients with early stage lung cancer. The original Indiana University phase II trial evaluating three fraction SBRT with a total dose of 60-66 ...

Eligibility Criteria

Inclusion

  • Age≥ 18 at time of consent
  • Karnofsky Performance Status (KPS) \> 40
  • Ability to provide written informed consent and HIPAA authorization
  • Clinical or pathological diagnosis of primary lung cancer or metastasis to the lung
  • Tumors must be located within 2 cm from the chest wall, defined as the inner border of the 2-cm lung expansion volume (per TG101)
  • Plan to receive Lung SBRT

Exclusion

  • Patients with tumors with \> 50% overlap between respiratory states based on CT simulation will not be eligible for this study
  • Previous radiation therapy to the same site per investigator discretion
  • Inability to comply with treatment or standard of care follow up per investigator discretion

Key Trial Info

Start Date :

October 2 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2024

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT04507828

Start Date

October 2 2020

End Date

December 30 2024

Last Update

April 1 2025

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Indiana University Hospital / IU Simon Cancer Center

Indianapolis, Indiana, United States, 46202