Status:

COMPLETED

The Role of Micro Nutrient Supplement in Improvement of the Sperm DNA Fragmentation

Lead Sponsor:

Hue University of Medicine and Pharmacy

Conditions:

Infertility, Male

Eligibility:

MALE

18-60 years

Phase:

NA

Brief Summary

Male from infertile couples are tested for semen analysis and sperm DNA fragmentation. Any case with high DNA fragmentation index (DFI) will be randomized indicated for multi-micro nutrient supplement...

Detailed Description

Higher DFI is correlated with poor embryo development, lower implantation rate in intracytoplasmic sperm injection (ICSI) cycles and higher miscarriage rate. The effectiveness of micro nutrients (PRO...

Eligibility Criteria

Inclusion

  • \- Male from infertile couples

Exclusion

  • Men with acute systemic diseases
  • acute urinary tract infection
  • hepatic function disorders
  • malignant diseases
  • retrograde ejaculation
  • azoospermia

Key Trial Info

Start Date :

November 18 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2021

Estimated Enrollment :

71 Patients enrolled

Trial Details

Trial ID

NCT04509583

Start Date

November 18 2019

End Date

December 30 2021

Last Update

June 22 2023

Active Locations (1)

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Hue University of Medicine and Pharmacy, Hue University

Huế, Thua Thien, Vietnam, 530000