Status:
COMPLETED
Effects of Anesthetic Methods on Hepatic Cancer Cell Function in Vitro
Lead Sponsor:
RenJi Hospital
Conditions:
Hepatocellular Carcinoma
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Numerous studies find that anesthetic methods may influence the recurrence of tumor and the overall survival of patients after primary cancer surgery. Radiofrequency (RF) ablation is now widely used i...
Detailed Description
Patients diagnosed with hepatocellular carcinoma (HCC) undergoing elective radiofrequency (RF) ablation surgery will be randomly allocated to general anesthesia(GA) group or local anesthesia(LA) group...
Eligibility Criteria
Inclusion
- 18 to 65 years old
- ASA grade I-III
- Diagnosed with a single primary liver tumor of 3cm or smaller
- Is scheduled for elective radiofrequency ablation surgery
- With no macro-vascular invasion, no lymph node or extrahepatic metastases
- Child-Pugh Class A or B
Exclusion
- a history of liver surgery previously (including radiofrequency ablation)
- severe systemic disease (heart, lung, kidney, or immune system)
- INR\>1.5 or platelet count \<45,000 cells/mm3
- a history of addiction to opioids;
- Disagree to participate the trial
Key Trial Info
Start Date :
August 20 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 28 2020
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT04510935
Start Date
August 20 2020
End Date
December 28 2020
Last Update
January 8 2021
Active Locations (1)
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1
Renji Hospital affliated to Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China, 200127