Status:

COMPLETED

The Study of Pharmacokinetics of Levetiracetam in Patients Undergoing Intermittent Hemodialysis

Lead Sponsor:

Phramongkutklao College of Medicine and Hospital

Collaborating Sponsors:

Silpakorn University

Conditions:

Seizures

Eligibility:

All Genders

18+ years

Brief Summary

Levetiracetam (LEV) is one of second-generation antiepileptic drugs that has been used to treat partial and generalized epilepsy. LEV is eliminated from the systemic circulation by renal excretion. Th...

Eligibility Criteria

Inclusion

  • Patients who were at least 18 years old.
  • Patients who were diagnosed with seizure.
  • Patients who were undergoing intermittent hemodialysis and were treated with intravenous Levetiracetam not less than 2 days

Exclusion

  • Patients who were pregnant or lactating
  • Patients who were treated with intravenous Levetiracetam more than once a day
  • Patients who were undergoing sustained low efficiency dialysis (SLED)
  • Patients who have intermittent dialysis duration less than 3 hours

Key Trial Info

Start Date :

November 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 10 2019

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT04511676

Start Date

November 1 2018

End Date

October 10 2019

Last Update

August 13 2020

Active Locations (1)

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Pharmongkutklao Hospital

Ratchathewi, Bangkok, Thailand, 10400