Status:

COMPLETED

Endothelial Microparticles as Potential Biomarkers of Endothelial Dysfunction

Lead Sponsor:

Universiti Sains Malaysia

Conditions:

Endothelial Dysfunction

Eligibility:

All Genders

35-70 years

Brief Summary

Endothelial microparticles (EMP) have a promising role as a diagnostic and prognostic tool in the assessment of endothelial function. This study compares the levels of EMP in hypercholesterolaemia pat...

Detailed Description

General study objective To evaluate EMP as a simple diagnostic tool in assessing endothelial function in hypercholesterolaemic patients. Specific objectives: 1. To compare the levels of EMP ( Clust...

Eligibility Criteria

Inclusion

  • Hypercholesterolaemia: ( LDL \>4.1 mmol/l)
  • Age 35 years and above
  • Agreeable to the treatment with statin if indicated

Exclusion

  • Pregnancy and breast feeding
  • Serious medical illness eg kidney failure, liver failure, stroke and malignancy.
  • Arrythmias
  • Contraindicated to statin

Key Trial Info

Start Date :

October 13 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2022

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT04512404

Start Date

October 13 2016

End Date

May 1 2022

Last Update

November 8 2022

Active Locations (1)

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Universiti Sains Malaysia

Kubang Kerian, Kelantan, Malaysia, 16150