Status:
UNKNOWN
The Short-term Efficacy of Novel NTDP-RFA in the Treatment of Small HCC With Cirrhosis.
Lead Sponsor:
Southwest Hospital, China
Conditions:
Hepatocellular Carcinoma Stage I
Radiofrequency Ablation
Eligibility:
All Genders
18-70 years
Brief Summary
To evaluate the short-term efficacy of novel no-touch combined directional perfusion radiofrequency ablation in the treatment of small hepatocellular carcinoma with cirrhosis.
Detailed Description
Liver cancer is the fourth leading cause of cancer-related deaths globally. Hepatocellular carcinoma (HCC) accounts for 70% to 85% of primary HCC and is the leading cause of death in patients with cir...
Eligibility Criteria
Inclusion
- Primary hepatocellular carcinoma with a background of cirrhosis
- Single shot with diameter ≤ 3cm
- The tumor did not invade portal vein, hepatic vein trunk and secondary branches
- Child Pugh A/B
- ICG-R15 ≤ 30%
- 18-70 years old
- The follow-up time reached 2 years
Exclusion
- The follow-up time is less than 2 years
- multiple lesions or diameter \> 3cm
- Previous history of upper gastrointestinal bleeding or severe hypersplenism
- Patients with extrahepatic or lymph node metastasis
- Wish to receive liver transplantation and hepatectomy
- The lesion is adjacent to the gallbladder, important blood vessels and bile ducts in the hilum of the liver and important organs around
- severe bleeding tendency, platelet count \< 50 × 10\^9/L, or prothrombin time prolonged \> 3s
- Other anti-tumor therapies were accepted before surgery
Key Trial Info
Start Date :
January 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04513119
Start Date
January 1 2017
End Date
August 31 2022
Last Update
August 14 2020
Active Locations (2)
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1
Institute of hepatobiliary surgery,Southwest Hospital
Chongqing, Chongqing Municipality, China, 400038
2
Institute of hepatobiliary surgery,Southwest Hospital
Chongqing, Chongqing Municipality, China, 400038