Status:
WITHDRAWN
Targeted Intervention Study of DTMS on Impaired Insight in Early Psychosis
Lead Sponsor:
Shanghai Mental Health Center
Conditions:
Impaired Insight
Eligibility:
All Genders
15-35 years
Phase:
NA
Brief Summary
Impaired insight is a key factor in the conversion of high-risk individuals to schizophrenia, but there is a lack of targeted interventions. We found that an electroencephalogram (EEG) signal reflecti...
Detailed Description
The study will conduct randomized and controlled experimental design, including deep transcranial magnetic stimulation (dTMS) and sham stimulation (SH-dTMS). Each included participant will be given in...
Eligibility Criteria
Inclusion
- 14\~35 years old;
- Meet the criteria of clinical high risk for psychosis or meet the DSM-V diagnostic criteria for schizophrenia;
- Meeting the following definition of impaired insight;
- Having completed at least six years of primary education;
- Being able to give informed consent, oral or written. Patients under 18 years old give oral consent and their next of kin or legal guardians give written consent.
Exclusion
- Participating in any other clinical intervention research;
- Meeting the diagnostic criteria of psychotic disorders (including affective disorders);
- Threshold symptoms are induced by other mental disorders or psychoactive substances;
- Undergoing anti-psychotic medication for more than 2 weeks;
- Being diagnosed as organic brain diseases, or severe somatic diseases;
- Had Experienced traumatic brain injury, and got scores of 7;
- Dementia, or mental retardation (IQ\<70);
- Being a condition of scalp infection;
- A pacemaker or other metal implants in the body, pregnancy, or claustrophobia.
Key Trial Info
Start Date :
January 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2027
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04513132
Start Date
January 1 2024
End Date
December 31 2027
Last Update
December 24 2024
Active Locations (1)
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1
Shanghai Mental Health Center
Shanghai, Shanghai Municipality, China, 200030