Status:
ACTIVE_NOT_RECRUITING
CPAP in AF Patients With OSA
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Atrial Fibrillation
Sleep Apnea
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Obstructive sleep apnea is associated with atrial fibrillation. This study is to evaluate the effect of continuous positive airway pressure on the burden of atrial fibrillation in the patients with ob...
Detailed Description
Traditional risk factors for AF were established from the original Framingham Heart Study cohort which showed aging, hypertension, congestive heart failure, coronary artery disease, valvular heart dis...
Eligibility Criteria
Inclusion
- men or women aged 18 to 80 years
- paroxysmal AF, diagnosed based on the ACC/AHA/HRS 2014 guideline, and is defined as AF that terminates spontaneously or with intervention within 7 d of onset either by 12-lead EKG, 24-hr Holter, or 14-day ECG monitor.
- OSA, defined as an AHI\>15/hr of sleep, of which \>50% of events are obstructive.
- Informed consent signed
Exclusion
- Moderate-severe valvular heart diseases (regurgitation or stenosis)
- post heart surgery
- Uncontrolled systemic hypertension or pulmonary hypertension
- Use of psychoactive or other drugs that could influence breathing patterns
- Current use of CPAP treatment
- Epworth sleepiness scale\>10
- Congestive heart failure (LVEF≦45%)
- Chronic obstructive pulmonary disease
- History of stroke or neuromuscular disease
- Severe insomnia
Key Trial Info
Start Date :
August 7 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04513483
Start Date
August 7 2020
End Date
December 31 2026
Last Update
July 20 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Taiwan University Hospital
Taipei, Taiwan