Status:

COMPLETED

Convalescent Plasma for COVID-19 Patients

Lead Sponsor:

Vinmec Research Institute of Stem Cell and Gene Technology

Collaborating Sponsors:

National Institute of Hygiene and Epidemiology, Vietnam

National Hospital for Tropical Diseases, Hanoi, Vietnam

Conditions:

COVID 19

Eligibility:

All Genders

18-75 years

Phase:

EARLY_PHASE1

Brief Summary

The investigators propose to evaluate intravenous administration of convalescent plasma (CP) obtained from COVID19 survivors in COVID19 patients who are in the medium stage. Supportive data exist for ...

Detailed Description

Coronaviruses are among the most common causes of the common cold in humans.1,2 In recent decades, coronavirus has caused several epidemic worldwide with a vast number of deaths such as severe acute r...

Eligibility Criteria

Inclusion

  • Age 18-75 years
  • SARS-CoV-19 PCR positive
  • Medium stage
  • Time from onset to screening ≤ 21 days, the SARS-CoV-2 test is still positive

Exclusion

  • Patients with a history of autoimmune disease or IgA deficiency
  • Patients with a history of allergy
  • Multi-organ/system failure
  • Pregnant or breastfeeding at the time of study
  • Cancer, history of heart failure, stroke, bronchial asthma
  • Multi-organ/system failure with indications for dialysis, severe hypoxia, failure with conventional treatment methods, indications for ECMO.
  • The patient is infected with multidrug-resistant bacteria.
  • The patient is participating in another study.
  • Time from onset to screening\> 21 days

Key Trial Info

Start Date :

August 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2021

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT04516954

Start Date

August 1 2020

End Date

April 30 2021

Last Update

June 6 2024

Active Locations (1)

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Vinmec Research Institute of Stem cell and Gene Technology

Hanoi, Vietnam, 10000