Status:

RECRUITING

Biomarkers Impact Evaluation on the Post-transplant Immune Response After Allografting of Hematopoietic Stem Cells

Lead Sponsor:

Centre Hospitalier Universitaire de Saint Etienne

Collaborating Sponsors:

Institut de Cancérologie de la Loire

Jean Monnet University

Conditions:

Malignant Hemopathy

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Chemotherapy or targeted therapy are usually used to treat hematological pathologies. Despite of medical improvement, some of these pathologies present drug resistances, or high risk of relapse. Hemat...

Detailed Description

Chemotherapy or targeted therapy are usually used to treat hematological pathologies. Despite of medical improvement, some of these pathologies present drug resistances, or high risk of relapse. Hemat...

Eligibility Criteria

Inclusion

  • Adult patient, over 18 years of age, suffering from a malignant hemopathy (without exception),
  • Patient for whom an allogeneic hematopoietic stem cell transplant from a related or unrelated donor is indicated,
  • Signed informed consent,
  • Patient covered by a social security scheme.

Exclusion

  • Allogeneic hematopoietic stem cell transplantation from cord blood or haplo-identical transplant,
  • Allogeneic transplant with post-transplant cyclophosphamide treatment,
  • Allograft with sequential conditioning.

Key Trial Info

Start Date :

May 25 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 30 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04517656

Start Date

May 25 2022

End Date

September 30 2026

Last Update

April 9 2025

Active Locations (1)

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1

CHU de Saint-Etienne

Saint-Etienne, France, 42055