Status:

RECRUITING

Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy

Lead Sponsor:

Michigan State University

Collaborating Sponsors:

McLaren Health Care

Conditions:

Pregnancy Related

Labor; Poor

Eligibility:

FEMALE

18-42 years

Phase:

NA

Brief Summary

Today it remains a challenge to successfully both halt and induce labor progression. Induction of labor is a common obstetric intervention that 1 in 4 women will experience. The goal of induction of l...

Detailed Description

Overview of study layout The indicated prenatal visit weeks are approximate time points. The prenatal visit only needs to occur prior to the sample collection time point. Time point 1 (First interac...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Are pregnant
  • Are 18-42 years old
  • Medically cleared for participation by Medical Investigator
  • Willingness to allow the study access to information in the participant's medical record
  • Willingness to be notified of incidental findings from study procedures
  • Willingness to measure and report on lighting conditions during specified time periods
  • Willingness to use a uterine contraction home monitor system, and report results
  • Willingness to adapt lighting during studies in home and/or hospital
  • Willingness to wear blue-filter glasses if requested
  • Willingness to report use of melatonin (for sleep)
  • Willingness to stop melatonin use if requested
  • Exclusion criteria
  • Pre-pregnancy BMI \>36kg/m2
  • HIV or AIDS (self-reported)
  • Severe anemia (hemoglobin \<8g/dL and/or hematocrit \<24%)
  • History or current psychotic disorder or diagnosis of a current major depressive episode or bipolar disorder
  • Current use of one or more of the following medications: metformin, systemic steroids, antipsychotic agents (e.g., Abilify, Haldol, Risperdal, Seroquel, Zyprexa), anti-seizure medications or mood stabilizers that would be expected to have a significant impact on body weight (e.g., Depakote, Lamictal, Lithium, Neurontin, Tegretol, Topamax, Keppra), medications for ADHD including amphetamines and methylphenidate
  • Continued use of weight loss medication including OTC and dietary supplements for weight loss (e.g., Adipex, Suprenza, Tenuate, Xenical, Alli, conjugated linoleic acid, Hoodia, Green tea extract, Guar gum, HydroxyCut, Sensa, Corti-slim, Chromium, chitosan, Bitter orange) Other Exclusion Criteria
  • Recent history of or currently smoking, drinking alcohol or abusing drugs (prescription or recreational)
  • Plans to move out of the study area within the next year or plans to be out of the study area for more than 8 weeks in the next 12 months
  • Planned termination of pregnancy

Exclusion

    Key Trial Info

    Start Date :

    September 1 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    September 1 2029

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT04521972

    Start Date

    September 1 2025

    End Date

    September 1 2029

    Last Update

    September 18 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Michigan State University

    East Lansing, Michigan, United States, 48824