Status:
COMPLETED
NAC Supplementation and Soccer Specific Performance
Lead Sponsor:
University of Thessaly
Conditions:
Skeletal Muscle Damage
Exercise-induced Aseptic Inflammation
Eligibility:
MALE
18-28 years
Phase:
NA
Brief Summary
In this investigation the investigators utilized NAC supplementation to boost GSH availability during an one-week-microcycle consisting of three soccer games, in order to test the hypotheses that: i) ...
Detailed Description
After exercise-induced muscle microtrauma the thiol/disulfide couple of reduced (GSH) and oxidized glutathione (GSSG) is a key regulator of important transcriptional pathways that control the inflamma...
Eligibility Criteria
Inclusion
- Participation at elite level (top three division leagues) of soccer competition for at least five years
- Abstained from consumption of performance-enhancing supplements, antioxidant supplements and medications (for at least 6 months before and during the study)
- Participation in at least six two-hour training sessions and one match per week
- Non-smokers
Exclusion
- A known NAC intolerance or allergy
- A recent febrile illness
- History of muscle lesion
- Lower limb trauma
- Metabolic diseases
Key Trial Info
Start Date :
April 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04523675
Start Date
April 1 2016
End Date
December 1 2016
Last Update
August 21 2020
Active Locations (1)
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1
Exercise Biochemistry Laboratory, School of Physical Education & Sports Sciences, University of Thessaly
Trikala, Greece, 42100