Status:

UNKNOWN

Early Diagnosis of Oxaliplatin-induced Portal Hypertension

Lead Sponsor:

Shanghai Zhongshan Hospital

Conditions:

Gastroesophageal Varices

Colorectal Cancer

Eligibility:

All Genders

18-75 years

Brief Summary

Oxaliplatin has been used as the first choice for the adjuvant chemotherapy of colorectal cancer and it has significantly improved the outcomes in patients with colorectal cancer. However, hepatotoxic...

Eligibility Criteria

Inclusion

  • Male or female patients aged 18-75
  • Had a history of oxaliplatin-based chemotherapy for the treatment of colorectal cancer surgery;

Exclusion

  • Combined known etiologies of chronic liver disease, including hepatitis, primary biliary cirrhosis, schistosomiasis, and non-alcoholic fatty liver disease.
  • With colorectal cancer required further anti-tumor treatment

Key Trial Info

Start Date :

August 31 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2022

Estimated Enrollment :

370 Patients enrolled

Trial Details

Trial ID

NCT04524650

Start Date

August 31 2020

End Date

September 30 2022

Last Update

August 28 2020

Active Locations (1)

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Department of Gastroenterology and Hepatology

Shanghai, Shanghai Municipality, China, 200032