Status:
COMPLETED
Morphological Abnormalities of the Olfactory Bulb on MRI and Olfactometry in Anosmic Versus Normosmic COVID-19 Patients
Lead Sponsor:
Hopital Foch
Collaborating Sponsors:
Hôpital Raymond Poincaré
Conditions:
Olfaction Disorders
COVID-19
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Olfactory and gustatory disorders are prevalent symptoms in European COVID-19 patients. This study aimed to detect these disturbances among positive COVID-19 patients (symptom not initially highlighte...
Detailed Description
Several medical teams have recently shown that disturbances of smell and taste are common and can be a precursor and even an isolated sign of COVID-19 involvement. Preliminary results suggest the pres...
Eligibility Criteria
Inclusion
- Patient aged 18 or over
- Patient with or without a sense of smell diagnosed with a positive COVID-19 PCR test by nasopharyngeal swab in one of the investigation centers
- Patient who has already undergone cerebral MRI and olfactometry, as part of their routine care, within 3 days of being diagnosed with COVID-19+ or who agrees to undergo cerebral MRI and olfactometry within 3 days of being diagnosed with COVID-19+.
- Patient who signed a consent form
- Patient being affiliated to a Health Insurance plan
Exclusion
- History of chronic rhino-sinusitis with or without polyp (s)
- History of major craniofacial trauma that led to loss of smell
- History of chronic sense of smell
- Diagnosis of Parkinson's disease or Alzheimer's disease
- Refusal to perform the 3 MRIs
- Refusal to participate in the study
- Pregnant, parturient or lactating woman
- Patient with contraindications to performing MRI
- Patient not speaking or understanding French
- Patient deprived of liberty or under guardianship
Key Trial Info
Start Date :
September 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 3 2021
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT04526054
Start Date
September 3 2020
End Date
September 3 2021
Last Update
August 3 2022
Active Locations (2)
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1
Hopital Raymond Poincare
Garches, France, 92380
2
Hopital Foch
Suresnes, Île-de-France Region, France, 92150