Status:
COMPLETED
Reducing the Incidence of VAP in Critically Ill Children and Assessment of Oral Care With CHX
Lead Sponsor:
Istanbul Medeniyet University
Conditions:
Ventilator Associated Pneumonia
Eligibility:
All Genders
1-18 years
Phase:
NA
Brief Summary
This was a single-centered, randomized, placebo-controlled double-blind clinical trial conducted in the pediatric intensive care unit (PICU), in patients who were aged 1 month to 18 years, needing MV ...
Detailed Description
Patients were randomized into two groups receiving CHX (0.12%) or placebo (0.9% NaCl) and followed for VAP development. All patients were consecutively randomized (1:1) to receive either 0.12% CHX rin...
Eligibility Criteria
Inclusion
- aged 1 month to 18 years
- needing MV for at least 48 hours
- PICU patients
Exclusion
- not consenting to participate in the study
- known hypersensitivity to CHX
- presence of tracheotomy,
- undergoing MV for less than 48 hours
- having received MV for more than 24 hours prior to PICU admission
- readmission to PICU
- suspected or diagnosed immunodeficiency
- history of malignant disease(active or at remission),
- being diagnosed with oral mucositis or periodontal disease
- chronic pulmonary and/or cardiac diseases
- having severe oral/facial trauma,
- use of immunosuppressive drugs (such as corticosteroids).
Key Trial Info
Start Date :
February 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2020
Estimated Enrollment :
138 Patients enrolled
Trial Details
Trial ID
NCT04527276
Start Date
February 1 2019
End Date
January 31 2020
Last Update
August 26 2020
Active Locations (1)
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1
Istanbul Medeniyet University
Istanbul, Turkey (Türkiye)