Status:
COMPLETED
A Prospective Study of Hypothyroidism After Radiotherapy for Breast Cancer
Lead Sponsor:
Chinese Academy of Medical Sciences
Conditions:
Breast Neoplasms
Hypothyroidism
Eligibility:
FEMALE
18-70 years
Brief Summary
This study is to prospectively investigate the incidence of hypothyroidism after postoperative radiotherapy and identify risk factors for development of hypothyroidism. Patients with breast cancer tre...
Detailed Description
Breast cancer patients treated with radiotherapy after surgery are prospectively enrolled. Thyroid function is evaluated mainly by the measurement of thyroid-stimulating hormone (TSH), free triiodo-th...
Eligibility Criteria
Inclusion
- Breast cancer patients at first diagnosis, patients who are treated with radiotherapy after breast conserving surgery or modified radical mastectomy, no medical history of hyperthyroidism, hypothyroidism or thyroiditis, have never taken thyroxine, no thyroid surgery.
Exclusion
- Absence or ectopic thyroid gland, previous radiotherapy of the neck, diseases of thalamus or pituitary, previous radiotherapy of thalamus or pituitary
Key Trial Info
Start Date :
November 15 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 24 2020
Estimated Enrollment :
729 Patients enrolled
Trial Details
Trial ID
NCT04528225
Start Date
November 15 2017
End Date
February 24 2020
Last Update
August 27 2020
Active Locations (1)
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1
Cancer Hospital, Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China, 100021