Status:

UNKNOWN

Efficacy and Tolerance of Liraglutide for Weight Loss in Obese Type 2 Diabetic Hemodialysis Patients

Lead Sponsor:

Fondation Hôpital Saint-Joseph

Conditions:

Diabetes Mellitus, Type 2

Hemodialysis

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

Brief Summary

Diabetes is the second leading cause of end stage renal disease in France (22% in the 2016 REIN register). In hemodialysis, its prevalence is higher, between 30-40% depending on the study. Associated ...

Eligibility Criteria

Inclusion

  • Patient aged ≥ 18 and \<70
  • Patient on hemodialysis for more than 6 months
  • Type 2 diabetic patient
  • Patient with a BMI\> 30 kg / m2 with a Temporary Contraindication for kidney transplant for renal transplant due to overweight by his graft center
  • Patient affiliated to a health insurance plan
  • French speaking patient
  • Patient having given free, informed and written consent

Exclusion

  • Patient with a Temporary Contraindication for kidney transplant for a cause other than overweight
  • Patient with personal or family history of thyroid medullary cancer
  • Patient with a history of acute or chronic pancreatitis
  • Patient who has already had hypersensitivity to liraglutide (or to any other component of the product)
  • Patient who has already had a severe digestive intolerance to taking GLP-1 receptor agonists (such as exenatide or lixisenatide)
  • Patient already included in an interventional risk research protocol (RIPH1)
  • Pregnant or lactating woman
  • Patient under guardianship or curatorship
  • Patient deprived of liberty

Key Trial Info

Start Date :

January 18 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2023

Estimated Enrollment :

18 Patients enrolled

Trial Details

Trial ID

NCT04529278

Start Date

January 18 2021

End Date

December 31 2023

Last Update

April 14 2023

Active Locations (4)

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Page 1 of 1 (4 locations)

1

AURA Paris Plaisance

Paris, Groupe Hospitalier Paris Saint-Joseph, France, 75014

2

Groupe Hospitalier Paris Saint-Joseph

Paris, France, 75014

3

Hôpital Bichat

Paris, France, 75018

4

AURA Paris Site de Saint Ouen

Saint-Ouen, France, 93400