Status:

UNKNOWN

Combination of Nimotuzumab and Radiotherapy for Recurrent Uterine Cervical Squamous Carcinoma

Lead Sponsor:

Lei Li

Conditions:

Recurrent Cervical Carcinoma

Radiotherapy

Eligibility:

FEMALE

18+ years

Phase:

PHASE2

Brief Summary

Patients with recurrent or metastatic uterine cervical squamous carcinoma have very poor prognosis. For eligible patients, radiotherapy remains the choice, which has the most effective impact on the s...

Eligibility Criteria

Inclusion

  • Female aged more than 18 years
  • Eastern Cooperative Oncology Group score 0-1
  • Pathological confirmed of uterine cervical squamous carcinoma
  • An interval of 3 months or more since the fulfilling of last treatment
  • At least one measurable lesion defined by Response Evaluation Criteria in Solid Tumors (RECIST) guideline 1.1
  • Anticipative survival period of 3 months or more
  • Lab testing within reference ranges
  • With appropriate contraception
  • Provided consents of participating the trial

Exclusion

  • With a history of exposure to other antiangiogenic agents
  • With other malignancies within past 3 years
  • With vital complications
  • With uncontrolled hypertension despite of medical treatment
  • With brain metastasis
  • With addiction to psychiatric medications or with mental disorders

Key Trial Info

Start Date :

December 19 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2023

Estimated Enrollment :

43 Patients enrolled

Trial Details

Trial ID

NCT04664244

Start Date

December 19 2020

End Date

December 31 2023

Last Update

December 22 2020

Active Locations (1)

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1

Lei Li

Beijing, Beijing Municipality, China, 100730