Status:

COMPLETED

Pharmacokinetics of Aqueous Dexamethasone

Lead Sponsor:

Frank A. Bucci, Jr., M.D.

Conditions:

Pharmacokinetics

Aqueous Dexamethasone

Eligibility:

All Genders

55+ years

Phase:

PHASE4

Brief Summary

The study is being done to measure the absorption of the DEXTENZA implant and inflammation concentration levels in the eye.

Eligibility Criteria

Inclusion

  • Male of female, aged 55 or older
  • Scheduled to undergo phacoemulsification with the intraocular lens (IOL) implantation for the treatment of cataract
  • Willing to comply with study instructions, agree to make study appointments, and complete the course of the study
  • Must sign an informed consent document indicating that they understand the purpose of and procedures required for the study and are willing to participate

Exclusion

  • Known allergy or contraindication to the test article or its components
  • Presence of any ocular abnormality or significant illness that, in the investigator's opinion, could affect the subject's health
  • History of any illness that could be expected to interfere with the study
  • Any condition that, in the opinion of the investigator, would compromise the well-being of the subject or study
  • May not be currently using topical or systemic steroids or NSAIDs during the course of the study or within 4 weeks prior to enrolling in the study other than Dextenza and Omidria
  • Subject has active corneal, conjunctival, or canalicular infections, including:
  • Epithelial herpes simplex keratitis (dendritic keratitis)
  • Vaccini
  • Varicella
  • Mycobacterial infections
  • Fungal diseases of the eye
  • Dacryocystitis

Key Trial Info

Start Date :

January 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 22 2022

Estimated Enrollment :

102 Patients enrolled

Trial Details

Trial ID

NCT04667507

Start Date

January 1 2021

End Date

June 22 2022

Last Update

October 21 2024

Active Locations (1)

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1

Bucci Laser Vision

Wilkes-Barre, Pennsylvania, United States, 18702