Status:
UNKNOWN
Effects of Intraoperative Vagal Block on Reducing the Postoperative Cough After Thoracic Surgery
Lead Sponsor:
Severance Hospital
Conditions:
Cough
Thoracic Surgery
Eligibility:
All Genders
19-80 years
Phase:
NA
Brief Summary
Randomized controlled study to investigate the role of intraoperative vagal nerve block for preventing the postoperative cough in patients who received the pulmonary resection for lung cancer
Detailed Description
The standard treatments for early primary lung cancer are surgical treatments (lobectomy and lymph node resection). The usual mortality rate of lung cancer surgery is 1-2%, and the incidence of compli...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists' physical status class Ⅲ
- Diagnosed with non-small cell lung cancer with clinical stage of I-IIIA
- Planned to undergo segmentectomy or lobectomy with mediastinal lymph node dissection
Exclusion
- chronic cough symptoms before surgery; a chronic cough (a cough lasting more than eight weeks)
- chemotherapy or chemoradiotherapy prior to surgery
- current smoker (patient should quit smoking at least 2 weeks before surgery)
- previously diagnosed with airway disease prior to surgery
- previously diagnosed with asthma prior to surgery
- patients with nervous system defects or psychiatric problems
- patients with severe cardiovascular disease, hepatological, or renal failure
Key Trial Info
Start Date :
December 29 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2023
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04672694
Start Date
December 29 2020
End Date
November 1 2023
Last Update
January 12 2021
Active Locations (1)
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1
Yonsei Severance Hospital
Seoul, South Korea