Status:

UNKNOWN

Regeneten Patch vs Standard Care in Partial Thickness Rotator Cuff Repair

Lead Sponsor:

Rothman Institute Orthopaedics

Conditions:

Rotator Cuff Tears

Shoulder Surgery

Eligibility:

All Genders

40-75 years

Phase:

NA

Brief Summary

Shoulder pain is a common complaint with the most common reason being tendinopathy and/or tearing of the rotator cuff. While many rotator cuff tears are often considered normal, age-related degenerati...

Eligibility Criteria

Inclusion

  • Males and females aged 40-75 years with a partial-thickness rotator cuff tear (50% or more) confirmed on MRI scan that, in combination with patient-report symptoms and clinical examination by the orthopaedic surgeon, would confirm the rotator cuff tear as the primary pathology driving pain, symptoms and functional disability .
  • Symptoms \> 3 months
  • Unsuccessful conservative treatment comprising of a corticosteroid injection (into the subacromial bursa) and physiotherapy (while it is acknowledged that a range of modalities may be available to patient's presenting with apparent symptomatic rotator cuff pathology, for the current study, physiotherapy has been defined specifically as a course of 'exercise-based' therapy specific to the individual patient, though generally comprising of exercises designed to strengthen the rotator cuff and scapula stabilizing musculature, improving flexibility and shoulder mobility)

Exclusion

  • Revision surgery
  • Cervical pathology
  • Adhesive capsulitis
  • Multi-tendon tears
  • Concomitant upper limb pathology (eg: arthritis, nerve compression)
  • Infection
  • Previous fracture
  • Instability
  • Pregnancy and lactation
  • Professional athlete
  • Worker's compensation or compensable claim
  • Substance abuse or current mental illness
  • Smoker
  • Adverse reaction to bovine derived products

Key Trial Info

Start Date :

December 30 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04673344

Start Date

December 30 2020

End Date

December 31 2021

Last Update

December 17 2020

Active Locations (1)

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Rothman Orthopaedic Institute

Philadelphia, Pennsylvania, United States, 19107