Status:
COMPLETED
Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients
Lead Sponsor:
Kasr El Aini Hospital
Collaborating Sponsors:
Mansoura University
Conditions:
Anesthesia, Spinal
Elderly
Eligibility:
All Genders
60-90 years
Phase:
NA
Brief Summary
Fentanyl is a safer alternative than morphine in the management of postoperative pain in elderly. However, pruritus, nausea and vomiting are unwanted side effects of intrathecal fentanyl administratio...
Detailed Description
The aim of this study is to evaluate the effect of adding low dose intathecal naloxone to bupivacaine - fentanyl spinal anesthesia in elderly patients scheduled for unilateral lower limb orthopedic su...
Eligibility Criteria
Inclusion
- Age ≥ 60y of either gender.
- ASA physical status III or below.
- Patients scheduled for elective unilateral lower limb orthopedic surgery.
Exclusion
- Morbid obese patients.
- Severe or uncompensated cardiovascular, renal, hepatic or endocrinal diseases.
- Allergy to one of the agents used.
- Severely altered consciousness level.
- Coagulopathy
- Increased intracranial pressure
- Neuromuscular diseases
- Severe spinal deformity
- Patients on opioid analgesics or opioid abuse
- Multi traumatized patients
- Patients with preoperative Mini Mental State Examination ( MMSE ) scoring \< 24
Key Trial Info
Start Date :
December 10 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 10 2021
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT04673812
Start Date
December 10 2020
End Date
March 10 2021
Last Update
March 16 2021
Active Locations (1)
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1
Kasralainy
Cairo, Egypt