Status:
COMPLETED
viTAmin K2 and rEcOVery From ExeRcise
Lead Sponsor:
University of Glasgow
Collaborating Sponsors:
Kappa Bioscience
Conditions:
Inflammation
Oxidative Stress
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of the current study, therefore, is to investigate the effects of vitamin K2 supplementation on the physiological responses to an acute bout of resistance exercise.
Eligibility Criteria
Inclusion
- Participant is able and willing to sign the Informed Consent From
- No plans to change lifestyle (activity and nutrition) during the study period
- Older group (n=40): 65 years of age or older.
- Younger group (n=40): Aged 18-40 years
Exclusion
- Not currently, or in the last year, participating in more than 1h per week of vigorous aerobic physical activity or any resistance exercise
- BMI \> 30 kg/m2
- diabetes
- severe cardiovascular disease
- seizure disorders
- liver disease
- uncontrolled hypertension (\>150/90mmHg at baseline measurement)
- cancer or cancer that has been in remission \<5 years
- ambulatory impairments which would limit ability to perform assessments of muscle function
- dementia
- currently taking Vitamin K2 supplements
- currently taking Vitamin K antagonists/anticoagulants (e.g. warfarin)
- current smoking
- history of drug abuse
- taking medication known to affect muscle (e.g. steroids).
Key Trial Info
Start Date :
April 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2023
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04676958
Start Date
April 1 2021
End Date
July 1 2023
Last Update
November 28 2023
Active Locations (2)
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1
University of Glasgow
Glasgow, United Kingdom, G12 8TA
2
Stuart Robert Gray
Glasgow, United Kingdom