Status:
COMPLETED
Mind-body Therapy (Remotely Delivered) for Knee Osteoarthritis
Lead Sponsor:
Tufts Medical Center
Conditions:
Knee Osteoarthritis
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
This proposal aims to provide crucial knowledge about the neurobiological mechanisms underlying Tai Chi mind-body therapy for knee osteoarthritis (OA). The central mechanism of knee OA pain will be in...
Detailed Description
The study will investigate the central mechanism of knee OA pain using brain imaging technology to evaluate how brain function and structure change in response to mind-body exercise over time. Tai Chi...
Eligibility Criteria
Inclusion
- Age 50 years or older
- Unilateral or bilateral Knee OA
- Fulfills the American College of Rheumatology Criteria for symptomatic knee OA
- Willing to undergo MRI at baseline and follow-up
- WOMAC pain subscale score ≥2 on weight-bearing questions
Exclusion
- Serious medical conditions limiting ability of patient to participate in the study such as, symptomatic cardiovascular, symptomatic pulmonary disease requiring supplemental oxygen, uncontrolled metabolic diseases, severe renal and liver disease
- Presence of any contraindications to fMRI scanning. Including but not limited to: cardiac pacemaker, metal implants, fear of closed spaces, pregnancy, weight \>300 lbs
Key Trial Info
Start Date :
September 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04678999
Start Date
September 1 2020
End Date
November 30 2022
Last Update
March 14 2023
Active Locations (1)
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1
Tufts Medical Center, Division of Rheumatology
Boston, Massachusetts, United States, 02111