Status:
ENROLLING_BY_INVITATION
Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related Disorders
Lead Sponsor:
Mayo Clinic
Conditions:
PSP
CBD
Eligibility:
All Genders
21+ years
Brief Summary
The investigators aim to learn more about symptoms suggestive of a neurodegenerative process.
Detailed Description
The investigators will recruit participants with symptoms suggestive of a neurodegenerative and/or related disease. Participants could be evaluated on a yearly basis, undergoing a baseline visit and p...
Eligibility Criteria
Inclusion
- All participants will be over the age of 21
- Have symptoms suggestive of a neurodegenerative and/or related disorder
Exclusion
- Participants will be excluded if they have any concurrent illnesses that could account for all of their symptoms, such as traumatic brain injury, encephalitis, strokes or developmental syndromes
- Women that are pregnant or post-partum and breast-feeding will be excluded
- Participants will be excluded if they have any of the following genetic conditions which can increase the chance of cancer: Cowden disease, Lynch syndrome, Hypogammaglobulinemia, Wiskott-Aldrich syndrome and Down's syndrome
- Participants will be excluded if MRI is contraindicated (metal in head, cardiac pace maker, etc), if there is severe claustrophobia, if there are conditions that may confound brain imaging studies (e.g. structural abnormalities, including subdural hematoma, intracranial neoplasm or large cortical infarcts)
- Participants will be excluded if they are medically unstable or are on medications that might affect brain structure or metabolism (e.g. chemotherapy)
Key Trial Info
Start Date :
November 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2050
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT04680130
Start Date
November 1 2020
End Date
November 1 2050
Last Update
November 21 2025
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905