Status:

UNKNOWN

Prophylactic Implantation of Biologic Mesh in Peritonitis

Lead Sponsor:

Azienda Ospedaliero-Universitaria di Parma

Conditions:

Incisional Hernia

Peritonitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Patients undergoing emergency surgery for peritonitis are at increased risk of abdominal wall-related complications. In patients with peritonitis the risk of incisional hernia (IH) is extremely elevat...

Eligibility Criteria

Inclusion

  • Patients aged \> 18 years old
  • Clinical and/or laboratory and/or radiological evidence/signs of peritonitis of any origin (peritoneal reactivity, positive Blumberg sign, fever, free air/fluid in abdominal cavity, leucocytosis, increased C-Reactive Protein (CRP), lactic dehydrogenase (LDH), tachycardia, tachypnea, clinical or radiological evidence/suspect of bowel ischemia)
  • Eventual strong suspect of possible bacterial translocation (reduction of the natural intestinal barrier against bacterial translocation, i.e. bowel ischemia, bowel overdistension, intestinal occlusion, etc.)
  • Surgical indication for midline laparotomy independently from eventual previous laparotomies
  • Informed consent

Exclusion

  • Patients aged \< 18 years old
  • Informed consent refusal
  • No Clinical and/or laboratory and/or radiological evidence/signs of peritonitis of any origin
  • Surgical indication for laparotomies other than midline one
  • Pregnancy.

Key Trial Info

Start Date :

December 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2023

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT04681326

Start Date

December 1 2020

End Date

December 1 2023

Last Update

December 23 2020

Active Locations (1)

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Azienda Ospedaliera-Universitaria di Parma

Parma, Italy, 43125