Status:
UNKNOWN
Bright Light Therapy as Possible Treatment Option for MS-Fatigue
Lead Sponsor:
Medical University of Vienna
Collaborating Sponsors:
National Bank of Austria
Conditions:
Multiple Sclerosis
Fatigue
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This study aims to investigate the effect of a 2-week trial of bright light therapy (BLT, 10.000 lx) on fatigue in multiple sclerosis (MS) patients. In this randomised placebo-controlled trial, the ef...
Detailed Description
Materials and methods: * visual analogue scale (4x/day for 6 weeks; measuring fatigue) * wrist actigraphy (6 weeks) * sleep diaries (6 weeks) * polysomnography (2x) * multiple sleep latency test (2x)...
Eligibility Criteria
Inclusion
- MS patients who suffer from fatigue
- Age between 18 and 65 years old
- FSS Score of 36 or greater
- ESS Score of 12 or greater
- MEQ Score between 31 and 69
- BDI Score lower than 19
- BAI Score lower than 27
- EDSS lower than 4
Exclusion
- sleep disorders (periodic limb movement disorders, obstructive or central sleep apnea, REM sleep behavior disorders)
- change of antidepressive/fatigue influencing/sleep influencing/photosensizing/MS medication within the preceding 4 weeks
- clinical MS-relapse within the preceding 4 weeks
- consumption of alcohol: more than 1 glass per day
- consumption of caffeine: more than 4 cups per day
- current shift work
- Jet lag (travelled across two or more time zones within 90 days before study screening
- Retinopathy or other visual diseases/abnormalties
- Traumatic brain injury within the preceding 5 years
- pregnant or lactating
- Participation in another clinical trial at the same time
Key Trial Info
Start Date :
December 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2022
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT04681586
Start Date
December 1 2019
End Date
January 1 2022
Last Update
December 23 2020
Active Locations (1)
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1
Medical University of Vienna
Vienna, Austria, 1090