Status:
COMPLETED
Social Cognition in Youth Who Have a First Degree Relative With Schizophrenia
Lead Sponsor:
The Royal Ottawa Mental Health Centre
Conditions:
Schizophrenia
Eligibility:
All Genders
15-35 years
Phase:
NA
Brief Summary
Social cognition is an individual's ability to perceive, process, understand, and react to other individuals in a social situation. Social cognition is impaired in individuals with schizophrenia, incl...
Detailed Description
All participants will complete a battery of social cognitive tests as well as an fMRI scan to explore the neuronal correlates underlying lower social cognitive functioning observed in FHR individuals....
Eligibility Criteria
Inclusion
- Between (or equal to) 15-35 years of age
- Ability to read/speak fluent English
- Diagnosis of SZ, schizoaffective disorder or schizophreniform confirmed for 1st degree relative by referring psychiatrist or two reliable informants (using the adapted FIGS questionnaire).
Exclusion
- No diagnosis of psychosis related disorder
- Significant neurological or medical disorders that may produce cognitive impairment
- Current epilepsy or previous history of seizures
- Previous head injury with current continuing symptoms (i.e., cognitive ability, dizziness, etc.)
- Recent history of substance abuse or dependence (within past 3 months)
- MRI contraindication (e.g. metallic head implant, history of seizure, pacemaker, pregnancy, etc.)
- Current IQ \< 70 as measured by the Wechsler Abbreviated Scale of Intelligence Scale (WASI)
Key Trial Info
Start Date :
July 21 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 22 2025
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT04681807
Start Date
July 21 2021
End Date
August 22 2025
Last Update
January 2 2026
Active Locations (1)
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1
The Royal Ottawa Mental Health Centre
Ottawa, Ontario, Canada, K1Z 7K4