Status:
COMPLETED
A Safety Study of LY3526318 in Healthy Participants
Lead Sponsor:
Eli Lilly and Company
Conditions:
Healthy
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
The main purpose of this study is to learn more about how the drug is absorbed in to the blood stream and how it is eliminated from the body. The safety and tolerability of LY3526318 will also be eval...
Eligibility Criteria
Inclusion
- Are overtly healthy males or females, as determined through medical history and physical examination
- Have a body mass index (BMI) between 18 and 32 kilograms per square meter (kg/m²)
- Have clinical laboratory test results within normal reference range
Exclusion
- Have a history or presence of medical illness including, but not limited to, cardiovascular, hepatic, respiratory, hematological, endocrine, psychiatric or neurological disease, convulsions, or any clinically significant laboratory abnormality
- Have an abnormality in the 12-lead electrocardiogram (ECG)
- Have a history of clinically significant multiple or severe drug allergies
- Show evidence of human immunodeficiency virus (HIV) and/or positive human HIV antibodies, hepatitis C and/or positive hepatitis C antibody, or hepatitis B and/or positive hepatitis B surface antigen.
- Have an abnormal blood pressure
- Have received treatment with biologic agents (such as monoclonal antibodies, including marketed drugs) within 3 months or 5 half-lives (whichever is longer)
- Are unwilling to stop herbal supplements, over the counter or prescription medicines
- Are currently enrolled in a clinical drug study or any other type of medical research judged not to be scientifically or medically compatible with this study.
- Participants with a history of drug abuse
Key Trial Info
Start Date :
December 29 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 21 2021
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT04682119
Start Date
December 29 2020
End Date
April 21 2021
Last Update
September 10 2025
Active Locations (1)
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1
PRA Health Sciences
Groningen, Netherlands, 9728