Status:
UNKNOWN
HPV Serum Level and FDG PET CT in Patients With Cervical Cancer Treated With Radical Radiochemotherapy
Lead Sponsor:
The Greater Poland Cancer Centre
Conditions:
Cervical Cancer
Eligibility:
FEMALE
18-85 years
Phase:
NA
Brief Summary
The main purpose of the study is to describe changes in plasma HPV DNA levels in patients with locally advanced cervical cancer during radical radiochemotherapy (CRT) and to correlate changes with res...
Detailed Description
Ninety-five per cent of cervical cancer cases are caused by persistent infections with carcinogenic HPVs. Locally advanced stage IB2 to IVA cervical cancers are treated with definitive chemoradiation ...
Eligibility Criteria
Inclusion
- Age Limits: more than 18Y Histologically confirmed squamous cell carcinoma, FIGO stage IB-IVA planned for radical radiochemotherapy Eastern Cooperative Oncology Group (ECOG) performance status 0,1,2
Exclusion
- Patients who have received any anticancer treatment for their cervical cancer. Eastern Cooperative Oncology Group (ECOG) performance status \> 2 Other cervical cancer tumor histologies (e.g. small cell, serous) Contraindications to 18FDG PET-CT Contraindication to radiochemotherapy Known pregnancy or lactating
Key Trial Info
Start Date :
June 15 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2024
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04683549
Start Date
June 15 2020
End Date
June 30 2024
Last Update
January 8 2024
Active Locations (1)
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1
Greater Poland Cancer Centre / Oncological Gynecology Clinic
Poznan, Greater Poland Voivodeship, Poland, 61-866