Status:
UNKNOWN
Increased Peri-implant Keratinized Mucosal Thickness at Different Operative Times
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Dental Implants
Peri-Implantitis
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Keratinized mucosa, which is composed of free gingiva and attached gingiva, is a barrier against bacterial invasion in oral cavity and provides good tissue sealing for periodontal environment. When th...
Eligibility Criteria
Inclusion
- No systemic diseases or pregnancy;
- The thickness of keratinized mucosa where the posterior tooth is missing is less than 2 mm;
- Full-mouth plaque score (FMPS) \< 20% (measured at four sites per tooth) and bleeding on probing score (BOP%) ≤25% (measured at six sites per tooth);
- Periodontal condition is stable, no probing depths ≥5 mm;
- No previous soft tissue augmentation procedure at experimental site;
- The patient has signed informed consent and accepts the operation of subepithelial connective tissue transplantation.
Exclusion
- Patients with uncontrolled hypertension;
- Patients with uncontrolled diabetes;
- Patients with insufficient oral hygiene and Untreated periodontitis;
- Pregnant or lactating women;
- Smoker;
- Patients with long-term (\> 6 months) use of glucocorticoids;
- History of malignancy, radiotherapy, or chemotherapy for malignancy within the past 5 years;
- Patients with severe cardiovascular problems;
- Patients with uncontrolled infectious or metabolic diseases;
- Patients with substance abuse.
Key Trial Info
Start Date :
May 27 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2023
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT04683991
Start Date
May 27 2021
End Date
December 31 2023
Last Update
January 5 2022
Active Locations (1)
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1
Department of Oral Medicine, the Second Affiliated Hospital, School of Medicine Zhejiang University
Hangzhou, Zhejiang, China, 310009