Status:

UNKNOWN

Open-label Study of Neuraminidase Inhibitor Treatment in STEMI Patients

Lead Sponsor:

Tongji Hospital

Conditions:

ST Elevation Myocardial Infarction

STEMI

Eligibility:

All Genders

18-75 years

Phase:

PHASE4

Brief Summary

Neuraminidase-1 can cause the removal of terminal sialic acid residues from the cell surface or serum sialyloconjugates. The level of Neu5Ac was positively related to the activity of neuraminidase-1. ...

Eligibility Criteria

Inclusion

  • Between the ages of 18 and 75, regardless of gender;
  • STEMI should be diagnosed by two attending physicians or above, including history, clinical symptoms and signs;
  • Participate voluntarily and sign informed consent, and can be followed up for more than one month.

Exclusion

  • Allergic to oseltamivir;
  • Creatinine clearance rate less than 60%;
  • Severe liver insufficiency;
  • Female patients who have or plan to become pregnant;
  • Life expectancy less than one year;
  • Patients refused to comply with the requirements of this study;
  • According to the discretion of investigator, the patient was unable to complete the study or comply with the requirements of the study (for administrative or other reasons).

Key Trial Info

Start Date :

March 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 31 2024

Estimated Enrollment :

382 Patients enrolled

Trial Details

Trial ID

NCT04684498

Start Date

March 1 2020

End Date

March 31 2024

Last Update

December 24 2020

Active Locations (1)

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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China, 430030