Status:

WITHDRAWN

Use of Hypochlorous Acid as Prophylaxis in Health Personnel at High Risk of Infection by SARS-CoV 2 (COVID19)

Lead Sponsor:

Hospital Universitario San Ignacio

Collaborating Sponsors:

Pontificia Universidad Javeriana

Conditions:

SARS-CoV Infection

Covid19

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

PHASE3

Brief Summary

The pandemic caused by SARS-CoV-2 is a global emergency present in 6 continents including 66 countries, incurring a shortage of effective and safe therapeutic alternatives that can contribute to reduc...

Detailed Description

Hypochlorous acid (HClO) is a powerful antimicrobial and antiviral used for the control of various infections, repair and washing of surgical wounds, as well as for disinfection of surfaces. In vivo, ...

Eligibility Criteria

Inclusion

  • Specialist physicians, resident physicians, medical students, and nursing personnel who work at the San Ignacio University Hospital.
  • Subjects of any sex over 18 years of age who work as health care personnel, in care services that care for patients with a suspected or confirmed diagnosis of COVID-19 and who are active during the study recruitment.
  • That they have not presented general symptoms such as malaise, fever, cough, dyspnea or muscle pain during the last 7 days.
  • Subjects negative to the antigen test for COVID-19.

Exclusion

  • Subjects considered as a resolved case of COVID-19 infection, according to guidelines from the Colombian National Institute of Health.
  • Health personnel with social distancing due to close contact without personal protective equipment with patients confirmed to be infected or taking any medication as a possible prophylaxis for COVID-19 (example: chloroquine, hydroxychloroquine, azithromycin)
  • Health workers who have permits or temporary withdrawal from their hospital work for more than one week during the month of the study.
  • Some type of allergy to chlorinated agents or hypersensitivity to HClO
  • Known diagnosis of upper airway respiratory disease where COVID-19 such as the common cold, sinusitis, pharyngitis, laryngotracheitis and epiglottitis or lower such as bronchiolitis, pneumonia, and mixed conditions have been ruled out.
  • Previous COVID19 infection determined by positive PCR or positive serum antibody titers.
  • Any condition that in the principal investigator's discretion renders the subject ineligible to participate in the study.

Key Trial Info

Start Date :

February 15 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 15 2021

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04684550

Start Date

February 15 2021

End Date

August 15 2021

Last Update

March 3 2023

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