Status:
UNKNOWN
Research on Voice Intelligent Monitoring Technology for Early Warning of Recurrence of Depression Disorder
Lead Sponsor:
Shanghai Mental Health Center
Conditions:
Depressive Disorder
Eligibility:
All Genders
18-65 years
Brief Summary
This study aims to collect the voice output of depression patients and healthy subjects, extract the acoustic and semantic parameters, compare the similarities and differences between the depression g...
Detailed Description
Case control study Clinical symptoms, speech behavior test, EEG data, near-infrared brain imaging data and facial expression data are collected from three groups of subjects (consolidation/maintenance...
Eligibility Criteria
Inclusion
- Patients with depression in the consolidation/maintenance phase
- 18-65 years old, no gender limit;
- Meet the DSM-5 diagnostic criteria for depression;
- Currently in the consolidation/maintenance phase, with stable condition, HAMD-17 \<7 points;
- Patients and their guardians understand the nature of this study and sign an informed consent form.
- Have sufficient audiovisual level to complete the necessary inspections for research;
- Han nationality
- Willing to participate in this research;
- Education level is junior high school and above.
- Patients with depression in acute onset:
- 18-65 years old, no gender limit;
- Meet the DSM-5 diagnostic criteria for depression;
- Currently in depressive episode, HAMD-17\>17 points;
- Patients and their guardians understand the nature of this study and sign an informed consent form.
- Have sufficient audiovisual level to complete the necessary inspections for research;
- Han nationality
- Willing to participate in this research;
- Education level is junior high school and above.
- Healthy control subjects
- 18-65 years old, no gender limit;
- Depressive symptoms have never occurred, and it does not meet the DSM-5 diagnostic criteria for depression or other mental disorders;
- No history of taking psychiatric drugs;
- Have sufficient audiovisual level to complete the necessary inspections for research;
- Willing to participate in this research;
- Education level is junior high school and above.
Exclusion
- Patients with depression in the consolidation/maintenance phase
- Patients with severe brain diseases and other severe physical diseases;
- Diagnosis of other mental diseases such as schizophrenia and bipolar disorder;
- There are negative beliefs or a higher risk of suicide;
- People who are addicted to psychoactive substances such as alcohol or drugs;
- Women who are pregnant or about to become pregnant recently, and women who are breastfeeding;
- There are metal implants in the body: there is a pacemaker, intracranial silver clip, metal denture, arterial stent, arterial clip, joint metal fixation, or other metal implant conditions, or non-right-handed (this standard (Only for MRI testers);
- Failure to sign or refuse to sign the informed consent form.
- Patients with depression in acute onset:
- Patients with severe brain diseases and other severe physical diseases;
- Diagnosis of other mental diseases such as schizophrenia and bipolar disorder;
- There are negative beliefs or a higher risk of suicide;
- People who are addicted to psychoactive substances such as alcohol or drugs;
- Women who are pregnant or about to become pregnant recently, and women who are breastfeeding;
- There are metal implants in the body: there is a pacemaker, intracranial silver clip, metal denture, arterial stent, arterial clip, joint metal fixation, or other metal implant conditions, or non-right-handed (this standard (Only for MRI testers);
- Failure to sign or refuse to sign the informed consent form.
- Healthy control subjects:
- Two lines and three generations of mental illness history;
- There are negative beliefs or a higher risk of suicide;
- Serious brain diseases and other severe physical diseases;
- Pregnant and lactating women;
- History of exposure to psychoactive substances such as alcohol or drugs;
- Failure to sign or refuse to sign the informed consent form.
- There is a metal implant in the body: there is a pacemaker, intracranial silver clip, metal denture, arterial stent, arterial clip, joint metal fixation, or other metal implant conditions, etc. (this standard is limited to MRI testers ).
Key Trial Info
Start Date :
December 31 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2022
Estimated Enrollment :
240 Patients enrolled
Trial Details
Trial ID
NCT04685083
Start Date
December 31 2020
End Date
December 31 2022
Last Update
May 19 2021
Active Locations (1)
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1
Shanghai Mental Health Center
Shanghai, Shanghai Municipality, China, 200030