Status:

ACTIVE_NOT_RECRUITING

REgiStry Of the NAtural History of recurreNt periCarditis in pEdiatric and Adult Patients

Lead Sponsor:

Kiniksa Pharmaceuticals International, plc

Collaborating Sponsors:

Kiniksa Pharmaceuticals (UK), Ltd.

Conditions:

Recurrent Pericarditis

Eligibility:

All Genders

7+ years

Brief Summary

The registry will focus on furthering the understanding of the natural history of recurrent pericarditis (RP), as well as document RP-related clinical, health-related quality of life (HRQoL), and econ...

Eligibility Criteria

Inclusion

  • ACTIVE RP PATIENTS
  • Select
  • Physician-confirmed (or confirmation in medical records) diagnosis of RP defined as an initial, acute, episode and at least one pericarditis recurrence after the initial acute episode
  • Experienced at least one pericarditis episode in the 3 years prior to inclusion
  • Under the care of a physician for the treatment and management of RP
  • Currently prescribed medication for RP
  • Select

Exclusion

  • Diagnosis of pericarditis secondary to tuberculosis (TB), cancer if not in full remission, post thoracic blunt trauma (e.g., motor-vehicle accidents), myocarditis, systemic autoimmune diseases, except SJIA and adult Still's disease, HIV
  • Appears to have an impairment (e.g., cognitive, hearing, visual) or insufficient English or Spanish proficiency that could interfere with ability to complete patient-completed assessments
  • Currently enrolled in a therapeutic investigational drug or device study
  • INACTIVE RP PATIENTS
  • Select Inclusion Criteria:
  • Physician-confirmed (or confirmation in medical records) diagnosis of RP defined as an initial, acute, episode and at least one pericarditis recurrence after the initial, acute episode
  • Patient had a last episode occurring at least 3 years and up to 5 years before registry inclusion
  • Resolution of RP symptoms confirmed with no further RP treatment for 3 years prior to registry enrollment
  • Select

Key Trial Info

Start Date :

March 16 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT04687358

Start Date

March 16 2021

End Date

February 1 2026

Last Update

April 29 2025

Active Locations (29)

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Page 1 of 8 (29 locations)

1

Alaska Heart & Vascular Institute

Anchorage, Alaska, United States, 99508

2

Pima Heart and Vascular

Tucson, Arizona, United States, 85718

3

University of California San Diego Medical Center

La Jolla, California, United States, 92093

4

Cedars-Sinai Medical Center

Los Angeles, California, United States, 90048