Status:

ACTIVE_NOT_RECRUITING

Mobile Subthreshold Exercise Program for Concussion--R01

Lead Sponsor:

Seattle Children's Hospital

Collaborating Sponsors:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Conditions:

Concussion, Brain

Concussion, Mild

Eligibility:

All Genders

11-18 years

Phase:

NA

Brief Summary

Approximately 1.9 million youth sustain a concussion each year, and up to 30% experience persistent post-concussive symptoms (PPCS) such as headache, dizziness, and difficulty focusing that continue f...

Detailed Description

The investigators will recruit n=200 youth 11-18 years old with PPCS. Youth will be randomized to 6 weeks of either usual care plus M-STEP (intervention) or usual care plus stretching (control). Youth...

Eligibility Criteria

Inclusion

  • Youth 11-18 years
  • Concussion occurring 1 week to 12 months prior to the start of the study and diagnosed by a clinician trained in concussion management consistent with the 2017 Berlin consensus definition of concussion ("A traumatic brain injury, induced by biomechanical forces")
  • Persistent post-concussive symptoms as defined by the presence of at least 3 concussive symptoms rated at least 2 or greater on the Health and Behavior Inventory (HBI) and a total score of at least 10
  • Can be located anywhere as all study procedures are remote

Exclusion

  • Youth not fluent in English or at least one Parent not fluent in English or Spanish
  • Other injuries or medical conditions in addition to concussion that have prompted a clinician to recommend against MVPA, such as concerning abnormalities on routine brain imaging
  • Youth who indicate that they are completing an average of 30 minutes per day or greater of physical activity that increases their heart rate (indicative of a minimal need for a physical activity intervention)
  • Youth who have previously engaged with a Physical Therapist to increase aerobic activity
  • Youth who have been fully cleared for sport

Key Trial Info

Start Date :

March 22 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2025

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04688255

Start Date

March 22 2021

End Date

October 1 2025

Last Update

May 16 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Seattle Childrens Hospital

Seattle, Washington, United States, 98104

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