Status:
COMPLETED
Cigarette Smoking in Non-alcoholic Steatohepatitis
Lead Sponsor:
Tehran University of Medical Sciences
Conditions:
Non-Alcoholic Fatty Liver Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This non-randomized clinical trial was performed to clarify the effect of cigarette smoking reduction on liver function and some anthropocentric indices in smoker patients with non-alcoholic steatohep...
Detailed Description
After excluding other causes of high aminotransferase level, participants with persistent elevated serum aminotransferase levels and evidence of fatty liver in ultrasonography were presumed to have no...
Eligibility Criteria
Inclusion
- Smokers with persistent elevated aminotransferase levels with the evidence of fatty liver in ultrasonography, who were referred to a gastroenterology clinic.
Exclusion
- alcohol use (more than 20 gram per day in men and 10 gram per day in women per day),
- heart disease (ischemic or congestive),
- hepatic disease (viral hepatitis, autoimmune hepatitis, wilson disease, hemochromatosis, liver mass lesion),
- renal disease (serum creatinine concentration of \> 1.5 mg/dl),
- any severe systemic co-morbidities, neoplasm,
- using any hepatotoxic medication during the past 3 months,
- pregnant or lactating women.
Key Trial Info
Start Date :
November 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2018
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT04688307
Start Date
November 1 2017
End Date
December 1 2018
Last Update
October 21 2021
Active Locations (2)
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1
Gastroenterology clinic, Sina hospital.
Tehran, Iran
2
Sina Hospital, TUMS
Tehran, Iran