Status:
COMPLETED
Cardiovascular Effects of Racemic Epinephrine Pellets
Lead Sponsor:
University of Washington
Conditions:
Epinephrine Causing Adverse Effects in Therapeutic Use
Eligibility:
All Genders
2-9 years
Phase:
PHASE2
PHASE3
Brief Summary
The primary aim of this study was to determine if topical racemic epinephrine pellets affect heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) or mean arterial pressure (M...
Detailed Description
Dental caries is the most common chronic disease of childhood. 3-6% of US children experience early childhood caries, a condition that may necessitate restorative dental treatment. Prefabricated crown...
Eligibility Criteria
Inclusion
- Children ages 2-9 years undergoing general anesthesia for comprehensive dental treatment at the University of Washington Center of Pediatric Dentistry.
- Healthy patients according to the American Society of Anesthesiologists (ASA) classification I or II.
- Patients who have caries lesions requiring prefabricated crowns on primary maxillary first molars #B and #I.
Exclusion
- Pediatric patients with any severe systemic illness (ASA Classification III or greater).
- Pediatric patients with known cardiac arrhythmia, cardiovascular disease, diabetes and thyroid disease.
- Patients who are taking anti-arrhythmic, antihypertensive, or ionotropic medications.
- Patients who would need pulpotomy or pulpectomy treatment on primary maxillary first molars #B and I.
Key Trial Info
Start Date :
June 10 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2019
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT04688346
Start Date
June 10 2019
End Date
November 30 2019
Last Update
May 13 2021
Active Locations (1)
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1
UW Center for Pediatric Dentistry
Seattle, Washington, United States, 98115