Status:
COMPLETED
Metabolomic Profiling of Erector Spinae Plane Block* for Breast Cancer Surgery
Lead Sponsor:
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Conditions:
Breast Cancer
Eligibility:
FEMALE
18-65 years
Brief Summary
Worldwide, breast cancer is the most common cancer among women, and its incidence and mortality rates are expected to increase significantly in the next years. It remains a major health problem. There...
Detailed Description
Breast cancer is the most frequently encountered surgery among all cancer surgeries. Although it is a well known procedure for anesthesiologists, it is still unclear whether anesthesiology effects imm...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Should be female
- Should be between 18-65 years old
- Diagnosed with unilateral primary breast cancer
- Are decided to have mastectomy surgery
- Stage 1-2 breast cancer (T0-1-2, N0-1, M0)
- Exclusion criteria from the:
- Being allergic to the anesthetics
- Previously had breast operation other than diagnostic biopsy
- Presence of a malignancy history on the other breast
- Diagnosed with Inflammatory breast cancer
- Having a risk score of The American Society of Anaesthesiologists (ASA) risk score 3 and above
- Contraindications for regional block(Allergies for local anesthetics, Anatomic application difficulties, Coagulopathies)
- Hormone usage
- NRS score greater than 3 before the operation
- Opioid or steroid usage before the operation
- Rheumatologic history
- Sickness or drug usage that might cause immunosuppression
- Chemotherapy and/or radiotherapy history
- Concomitant history of previous malignancy
- History of Coronary Artery Disease, Peripheral Vascular Disease that may affect VEGF
- Chronic smoking
- Chronic obstructive pulmonary disease
- Presence of infection at the time of surgery
- Hypothalamus, Pituitary, adrenal gland dysfunction
- Autoimmune diseases
Exclusion
Key Trial Info
Start Date :
February 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2021
Estimated Enrollment :
91 Patients enrolled
Trial Details
Trial ID
NCT04689945
Start Date
February 1 2021
End Date
October 1 2021
Last Update
January 19 2023
Active Locations (1)
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1
Dr.Abdurrahman Yurtaslan Ankara Oncology Train and Research Hospital
Ankara, Turkey (Türkiye), 06200