Status:
NOT_YET_RECRUITING
Cerebral Hemodynamics and Oxygenation in Critically Ill Patients
Lead Sponsor:
Centre Hospitalier Universitaire de Nice
Conditions:
Septic Shock
Eligibility:
All Genders
18+ years
Brief Summary
Critically-ill patients frequently experience marked changes in mean arterial pressure and carbon dioxide partial arterial pressure, the two major determinants of the cerebral blood flow. In addition,...
Eligibility Criteria
Inclusion
- Inclusion Criteria :
- Patients under mechanical ventilation and sedated within the first 72h of ventilation onset
- Indication to one of the studied therapeutics left at the discretion of the attending physician Exclusion criteria
- Age \< 18 years
- Pregnancy
- Inability to obtain a Doppler signal
- Medical history or clinical evidence of neurological disease
- Known severe carotid stenosis (\>70%)
- Significant cardiac arrhythmias
- Care-limitation decision.
Exclusion
Key Trial Info
Start Date :
March 1 2026
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2027
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04690530
Start Date
March 1 2026
End Date
March 1 2027
Last Update
April 10 2025
Active Locations (1)
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1
CHU de NICE
Nice, France, 06003