Status:

UNKNOWN

Effect of Low-dose Esketamine Combined With Target-controlled Infusion of Propofol for Painless Gastrointestinal Endoscopy

Lead Sponsor:

Tianjin Union Medical Center

Conditions:

Pain

Anesthesia

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Purpose: 1. To determine the efficacy of low-dose esketamine in painless gastrointestinal endoscopy. 2. To determine the safety of low-dose esketamine in painless gastrointestinal endoscopy. 3. To pro...

Detailed Description

Keeping spontaneous breathing anesthesia can provide patients with comfortable diagnosis and treatment experience during gastrointestinal endoscopy, which is a vital prerequisite for the large-scale d...

Eligibility Criteria

Inclusion

  • Subject's American Society of Anesthesiologists physical status is I-III.
  • Subject has no symptoms of allergy to anesthetics.
  • Subject has no contraindications for gastrointestinal endoscopy.
  • Subject has given written informed consent to participate.

Exclusion

  • Subject's BMI \<18 or \>30
  • Subject has poorly controlled or untreated hypertension.
  • Subject has severe ischemic heart disease.
  • Subject is an untreated or undertreated patient with hyperthyroidism.
  • Subject has used drugs that affect their central nervous system.
  • .Subject has mental illness.
  • .Subject has epilepsy.
  • .Subject has a history of chronic pain.
  • .Subject is pregnant or breast-feeding.

Key Trial Info

Start Date :

December 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2022

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT04691076

Start Date

December 1 2020

End Date

February 1 2022

Last Update

December 31 2020

Active Locations (1)

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1

Tianjin Union Medical Center

Tianjin, China, 300131