Status:
COMPLETED
Desflurane and Brain Relaxation in Craniotomy
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Supratentorial Tumor
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Optional brain relaxation improves the surgeon's operating conditions and is likely to minimize the degree of retraction injury ,with the potential for providing patients with a better outcome. The ch...
Detailed Description
To compare the effect of desflurane versus propofol combined with remifentanil anesthesia on brain relaxation in patients undergoing supratentorial tumor surgery with mild hyperventilation, and compar...
Eligibility Criteria
Inclusion
- 18-60 years
- Scheduled for elective craniotomy for supratentorial cerebral tumors
- ASA status I-III
- Glasgow score of 15
- No clinical signs of intracranial hypertension
- Preoperative brain imaging (CT or MRI) with midline shift less than 5mm
- Informed consent signed by patients
Exclusion
- Scheduled intraoperative motor evoked potential monitoring
- Patients with cerebral vascular diseases
- Uncontrolled cardiopulmonary disease
- Schedule to retain tracheal intubation after surgery
- Unable to comprehend and cooperate with the examination
- BMI \> 30 Kg/m-2
- Emergency surgery
- History of related anesthetic allergy
Key Trial Info
Start Date :
January 26 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 31 2021
Estimated Enrollment :
111 Patients enrolled
Trial Details
Trial ID
NCT04691128
Start Date
January 26 2021
End Date
August 31 2021
Last Update
October 26 2021
Active Locations (1)
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1
Beijing Tiantan Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100070