Status:
RECRUITING
Stellate Ganglion Block and Cerebral Vasospasm
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Aneurysmal Subarachnoid Hemorrhage
Stellate Ganglion Block
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
At present, cerebral vasospasm (cVS) is the main cause of delayed cerebral infarction (DCI), which leads to high disability and mortality rate after aneurysmal subarachnoid hemorrhage. As a consequenc...
Detailed Description
Cerebral vasospasm refers to the extensive segmental or diffuse contraction of cerebral vasculature after aSAH, and cerebral blood flow is significantly reduced, which can lead to delayed cerebral isc...
Eligibility Criteria
Inclusion
- Age range: 18-65 years old;
- Within 48 hours after onset of aSAH,and planning surgical treatment(aneurysm clipping);
- Preoperative Hunt-Hess grade 2-3
- Sign informed consent.
Exclusion
- ASA \> grade III;
- Patients with posterior circulation aneurysm, ophthalmic aneurysms or internal carotid aneurysms;
- patients with multiple aneurysms;
- Patients with severe coagulation dysfunction;
- Patients with trauma and local infection in the nerve block area;
- Local anatomic structure changes (neck structure changes caused by radiotherapy, chemotherapy and surgery);
- MCA stenosis or infarction was found by preoperative imaging;
- Patients with poor temporal window signal revealed by preoperative TCD (clear waveform image could not be obtained);
- Allergy to known local anesthetics;
- Pregnant and lactating women.
Key Trial Info
Start Date :
July 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2024
Estimated Enrollment :
202 Patients enrolled
Trial Details
Trial ID
NCT04691271
Start Date
July 1 2021
End Date
December 30 2024
Last Update
March 15 2024
Active Locations (1)
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1
Beijing Tiantan Hospital
Beijing, Beijing Municipality, China, 100070