Status:
COMPLETED
A Prospective Clinical Study to Explore Response to Prone Positioning in ARDS Patients
Lead Sponsor:
Rush University Medical Center
Conditions:
Covid19
ARDS
Eligibility:
All Genders
18+ years
Brief Summary
The proposed study will be conducted to investigate the mechanism of patients' responses to prone positioning with coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) and no...
Detailed Description
This is a prospective observational study of adult patients with coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS) and non-COVID-19 ARDS who are intubated, in the prone po...
Eligibility Criteria
Inclusion
- Adult subjects 18 years and older, diagnosis of ARDS
- endotracheally intubated and receiving assisted mechanical ventilation
- meet criteria for prone positioning: PaO2/FIO2 (P/F ratio) of ≤ 150 mm Hg with ventilator parameters of PEEP ≥ 10 cm H2O and FiO2 of .60
- receive an order for prone positioning.
Exclusion
- Pregnant
- Tracheostomy
- Receiving ECMO
- Palliative care
- Receive prone positioning more than once during intubation in an outside hospital
- Receive invasive ventilation in an outside hospital for more than 72 hours
Key Trial Info
Start Date :
January 31 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 6 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04692779
Start Date
January 31 2021
End Date
December 6 2024
Last Update
October 8 2025
Active Locations (1)
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1
Rush University Medical Center
Chicago, Illinois, United States, 60612