Status:
COMPLETED
Cannabis Inhalation: Effects on Cardiovascular Function During Rest and Exercise
Lead Sponsor:
Jamie Burr
Conditions:
Cannabis
Cardiovascular Risk Factor
Eligibility:
All Genders
19-45 years
Phase:
EARLY_PHASE1
Brief Summary
This two-phase project seeks to examine the cardiovascular response to consumption of cannabis variants of different cannabinoid composition through different methods (smoking vs. vaporizing), at rest...
Eligibility Criteria
Inclusion
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and availability for the duration of the study
- Male or female, aged 19-45yr
- In good general health as evidenced by medical history and free of chronic disease
- Must be experienced with cannabis use. This requires recreational cannabis use of a minimum of once per week in the past 30 days as confirmed by urine test
- Experience consuming cannabis recreationally by vaping dried cannabis
Exclusion
- Deemed unfit to exercise by the PARQ+.
- Current or past diagnoses of substance abuse disorder
- Failure of recreational substance urine screening test
- Current, past, or strong family history of psychosis, or has previously experienced a cannabis-related psychotic episode
- Current or past diagnoses of cannabis use disorder
- Current or past diagnoses of any mood or anxiety disorder
- Identified ECG abnormalities
- Systolic blood pressure exceeding 160mmHg
- Diastolic blood pressure exceeding 90mmHg
- Resting heart rate exceeding 100bpm, or lower than 40bpm
- Diagnosed with respiratory disease
- Diagnosed with cardiovascular disease
- Diagnosed with liver disease
- Diagnosed with kidney disease
- Is Pregnant or planning to be pregnant
- Currently taking prescription medication (excluding contraceptive medication)
- Is a cigarette smoker
Key Trial Info
Start Date :
September 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 16 2025
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT04693884
Start Date
September 1 2021
End Date
April 16 2025
Last Update
April 18 2025
Active Locations (1)
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1
University of Guelph
Guelph, Ontario, Canada, N1G2W1