Status:

UNKNOWN

A Multi-center Study to Determine the Prevalence and Influence of Pertussis on COPD Exacerbation in Shenzhen

Lead Sponsor:

Shenzhen People's Hospital

Conditions:

COPD Exacerbation

Pertussis

Eligibility:

All Genders

40-80 years

Brief Summary

A prospective, multi-center, observational clinical trail. Aim to evaluate the real incidence of chronic obstructive pulmonary disease (COPD) pertussis and the impact of pertussis on COPD exacerbation...

Detailed Description

1. Investigate the incidence and epidemiological characteristics of pertussis infection in COPD population. 2. To explore the relationship between pertussis infection and COPD exacerbation.

Eligibility Criteria

Inclusion

  • \- Clinical diagnosis of acute COPD

Exclusion

  • \- Major diseases except COPD; Significant abnormality in laboratory examination; Clinical diagnosis of lung cancer, bronchiectasis, pneumoconiosis or other simple restrictive ventilation dysfunction; Patients with a history of asthma, allergic rhinitis, or a blood eosinophil count of 2600/mm3 (0.6x10\^9/L) within 4 weeks; Currently suffering from active tuberculosis; Patients with life-threatening pulmonary embolism, or al-antitrypsin deficiency, or cystic fibrosis; Patients who have undergone lung resection.

Key Trial Info

Start Date :

January 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT04694430

Start Date

January 1 2021

End Date

December 31 2021

Last Update

January 5 2021

Active Locations (27)

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Page 1 of 7 (27 locations)

1

Fuyong people's Hospital of Baoan District, Shenzhen

Shenzhen, China

2

General Hospital of Shenzhen University

Shenzhen, China

3

Longhua Branch of Shenzhen People's Hospital

Shenzhen, China

4

Nanshan District People's Hospital

Shenzhen, China