Status:
RECRUITING
Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients
Lead Sponsor:
Lille Catholic University
Conditions:
Multiple Sclerosis
Memory
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The main goal of this study is to assess the effectiveness of a cognitive remediation program based on a "serious game" on the information processing speed evolution and the process of learning via ep...
Detailed Description
Cognitive impairment affects 40 to 70% multiple sclerosis patients. This condition is characterized by slower information processing, associated with deficits in episodic memory, attention and executi...
Eligibility Criteria
Inclusion
- Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005
- Age between ≥ 18 and ≤ 65 years old
- Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (\<5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test
- Have not had a definite relapse for at least 6 weeks
- Be at least 4 weeks away from a corticosteroid bolus
- Lack of neuroleptic treatment
- Patient with an Internet connection
- Signed informed consent
Exclusion
- Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment.
- Neuropsychological care
- Inability to receive oral and written information
- Inability to use the software (due in particular to motor and / or sensory difficulties),
- Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome
- Patient with severe anxiodepressive syndrome (BDI\> 27)
- Participation in an interventional study on cognitive functions
- Patient under legal protection, guardianship or curatorship
- Pregnant or breastfeeding women
Key Trial Info
Start Date :
October 8 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2027
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04694534
Start Date
October 8 2021
End Date
March 1 2027
Last Update
September 4 2025
Active Locations (6)
Enter a location and click search to find clinical trials sorted by distance.
1
CH Arras
Arras, Hauts-de-France, France, 62000
2
CH LENS
Lens, Hauts-de-France, France, 62300
3
CHRU
Lille, Hauts-de-France, France, 59000
4
Saint Vincent hospital
Lille, Hauts-de-France, France, 59000