Status:
UNKNOWN
The Effect of PPI in Preventing Gastroesophageal Reflux Disease of Seafarers
Lead Sponsor:
Fifth Affiliated Hospital, Sun Yat-Sen University
Conditions:
Gastroesophageal Reflux Disease
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
In view of the high incidence of GERD among seafarers and its continuing impact on the life quality of seafarers, it is necessary to use preventive treatment. At the same time, because both mental and...
Detailed Description
Gastroesophageal reflux disease (GERD) is one of the common digestive system diseases. However, at present, there are only sporadic reports on the diagnosis and treatment of seafarers' gastroesophagea...
Eligibility Criteria
Inclusion
- Agree to the implementation of this research and sign an informed consent form.
Exclusion
- PPI drugs were previously used to treat acid-related diseases or conditions (including peptic ulcer, non-variceal upper gastrointestinal hemorrhage, gastroesophageal reflux disease, Zollinger-Ellison syndrome, and functional dyspepsia, eradication of Helicobacter pylori) 2 weeks before enrollment).
- Those having a history of stomach surgery.
- Those who have alarm symptoms (recent weight loss for unknown reasons, such as 5% or more of the original weight loss in the first half of the year; Progressive dysphagia, anemia, hematemesis, melena, hematochezia）or physical examination shows abnormalities such as abdominal rebound pain, masses, etc.).
- Pregnant or lactating women.
- Serious diseases and complications that may interfere with the research, such as heart, liver, kidney, lung, peripheral or autonomic nervous diseases, diabetes, etc.
- Allergic to PPI drugs.
- Having a history of drug abuse.
Key Trial Info
Start Date :
July 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2021
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT04696783
Start Date
July 1 2021
End Date
November 1 2021
Last Update
January 6 2021
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